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Max-Planck-Institut für Experimentelle Medizin
Cathomas F, Azzinnari D, Bergamini G, Sigrist H, Buerge M, Hoop V, Wicki B, Goetze L, Soares S, Kukelova D, Seifritz E, Goebbels S, Nave KA, Said Ghandour M, Seoighe C, Hildebrandt T, Leparc G, Klein H, Stupka E, Hengerer B, Pryce CR (2018).
Oligodendrocyte gene expression is reduced by and influences effects of chronic social stress in mice.
Genes Brain Behav. [Epub ahead of print]

Thakurela S, Garding A, Jung RB, Müller C, Goebbels S, White R, Werner HB, Tiwari VK (2016).
The transcriptome of mouse central nervous system myelin.
Sci Rep. 6, 25828-25828

Weil MT, Möbius W, Winkler A, Ruhwedel T, Wrzos C, Romanelli E, Bennett JL, Enz L, Goebels N, Nave KA, Kerschensteiner M, Schaeren-Wiemers N, Stadelmann C, Simons M (2016).
Loss of Myelin Basic Protein Function Triggers Myelin Breakdown in Models of Demyelinating Diseases.
Cell Rep. 16, 314-322

Poggi G, Boretius S, Möbius W, Moschny N, Baudewig J, Ruhwedel T, Hassouna I, Wieser GL, Werner HB, Goebbels S, Nave KA, Ehrenreich H (2016).
Cortical network dysfunction caused by a subtle defect of myelination.
Glia 64, 2025-2040

Patzig J, Erwig MS, Tenzer S, Kusch K, Dibaj P, Möbius W, Goebbels S, Schaeren-Wiemers N, Nave KA, Werner HB (2016).
Septin/anillin filaments scaffold central nervous system myelin to accelerate nerve conduction.
Elife. 5, pii: e17119-pii: e17119

Goebbels S, Wieser GL, Pieper A, Spitzer S, Weege B, Yan K, Edgar JM, Yagensky O, Wichert SP, Agarwal A, Karram K, Renier N, Tessier-Lavigne M, Rossner MJ, Káradóttir RT, Nave KA (2016).
A neuronal PI(3,4,5)P(3)-dependent program of oligodendrocyte precursor recruitment and myelination.
Nat Neurosci. 20, 10-15

Jarjour AA, Boyd A, Dow LE, Holloway RK, Goebbels S, Humbert PO, Williams A, ffrench-Constant C. (2015).
The polarity protein Scribble regulates myelination and remyelination in the central nervous system
PLoS Biol 13, e1002107-e1002107

Snaidero N, Möbius W, Czopka T, Hekking LH, Mathisen C, Verkleij D, Goebbels S, Edgar J, Merkler D, Lyons DA, Nave KA, Simons M (2014).
Myelin Membrane Wrapping of CNS Axons by PI(3,4,5)P3-Dependent Polarized Growth at the Inner Tongue.
Cell 156, 277-290

Huang W, Zhao N, Bai X, Karram K, Trotter J, Goebbels S, Scheller A, Kirchhoff F (2014).
Novel NG2-CreERT2 knock-in mice demonstrate heterogeneous differentiation potential of NG2 glia during development.
Glia 62, 896-913

Hsia HE, Kumar R, Luca R, Takeda M, Courchet J, Nakashima J, Wu S, Goebbels S, An W, Eickholt BJ, Polleux F, Rotin D, Wu H, Rossner MJ, Bagni C, Rhee JS, Brose N, Kawabe H (2014).
Ubiquitin E3 ligase Nedd4-1 acts as a downstream target of PI3K/PTEN-mTORC1 signaling to promote neurite growth.
Proc Natl Acad Sci U S A. 111, 13205-13210

Bormuth I, Yan K, Yonemasu T, Gummert M, Zhang M, Wichert S, Grishina O, Pieper A, Zhang W, Goebbels S, Tarabykin V, Nave KA, Schwab MH (2013).
Neuronal Basic Helix-Loop-Helix Proteins Neurod2/6 Regulate Cortical Commissure Formation before Midline Interactions.
J Neurosci. 33, 641-651

Frühbeis C, Fröhlich D, Kuo WP, Amphornrat J, Thilemann S, Saab AS, Kirchhoff F, Möbius W, Goebbels S, Nave KA, Schneider A, Simons M, Klugmann M, Trotter J, Krämer-Albers EM (2013).
Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication.
PLoS Biol. 11, e1001604-e1001604

Hagemeyer N, Goebbels S, Papiol S, Kästner A, Hofer S, Begemann M, Gerwig UC, Boretius S, Wieser GL, Ronnenberg A, Gurvich A, Heckers SH, Frahm J, Nave KA, Ehrenreich H (2012).
A myelin gene causative of a catatonia-depression syndrome upon aging.
EMBO Mol Med. 4, 528-539

Goebbels S, Oltrogge JH, Wolfer S, Wieser GL, Nientiedt T, Pieper A, Ruhwedel T, Groszer M, Sereda MW, Nave KA (2012).
Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy.
EMBO Mol Med. 4, 486-499

Fünfschilling U, Supplie LM, Mahad D, Boretius S, Saab AS, Edgar J, Brinkmann BG, Kassmann CM, Tzvetanova ID, Möbius W, Diaz F, Meijer D, Suter U, Hamprecht B, Sereda MW, Moraes CT, Frahm J, Goebbels S, Nave KA (2012).
Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity.
Nature 485, 517-521

Gogishvili T, Lühder F, Kirstein F, Nieuwenhuizen NE, Goebbels S, Beer-Hammer S, Pfeffer K, Reuter S, Taube C, Brombacher F, Hünig T (2012).
Interruption of CD28-mediated costimulation during allergen challenge protects mice from allergic airway disease.
J Allergy Clin Immunol. 130, 1394-1403

Gogishvili T, Lühder F, Goebbels S, Beer-Hammer S, Pfeffer K, Hünig T (2012).
Cell-intrinsic and -extrinsic control of Treg-cell homeostasis and function revealed by induced CD28 deletion.
Eur J Immunol. 43, 188-193

Ochocinska MJ, Muñoz EM, Veleri S, Weller JL, Coon SL, Pozdeyev N, Iuvone PM, Goebbels S, Furukawa T, Klein DC (2012).
NeuroD1 is required for survival of photoreceptors but not pinealocytes: results from targeted gene deletion studies.
J Neurochem. 123, 44-59

Agarwal A, Dibaj P, Kassmann CM, Goebbels S, Nave KA, Schwab MH (2011).
In Vivo Imaging and Noninvasive Ablation of Pyramidal Neurons in Adult NEX-CreERT2 Mice.
Cereb Cortex. 22, 1473-1486

Reich A, Spering C, Gertz K, Harms C, Gerhardt E, Kronenberg G, Nave KA, Schwab M, Tauber SC, Drinkut A, Harms K, Beier CP, Voigt A, Göbbels S, Endres M, Schulz JB (2011).
Fas/CD95 regulatory protein Faim2 is neuroprotective after transient brain ischemia.
J Neurosci. 31, 225-233

Goebbels S, Oltrogge JH, Kemper R, Heilmann I, Bormuth I, Wolfer S, Wichert SP, Möbius W, Liu X, Lappe-Siefke C, Rossner MJ, Groszer M, Suter U, Frahm J, Boretius S, Nave KA (2010).
Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination.
J Neurosci. 30, 8953-8964

Bottelbergs A, Verheijden S, Hulshagen L, Gutmann DH, Goebbels S, Nave KA, Kassmann C, Baes M (2010).
Axonal integrity in the absence of functional peroxisomes from projection neurons and astrocytes.
Glia 143, 1532-1543

Quintes S, Goebbels S, Saher G, Schwab MH, Nave KA (2010).
Neuron-glia signaling and the protection of axon function by Schwann cells.
J Peripher Nerv Syst. 15, 10-16

Gu C, Stein GH, Pan N, Goebbels S, Hörnberg H, Nave KA, Herrera P, White P, Kaestner KH, Sussel L, Lee JE (2010).
Pancreatic beta cells require NeuroD to achieve and maintain functional maturity.
Cell Metab. 11, 298-310

Kawabe H, Neeb A, Dimova K, Young SM Jr, Takeda M, Katsurabayashi S, Mitkovski M, Malakhova OA, Zhang DE, Umikawa M, Kariya K, Goebbels S, Nave KA, Rosenmund C, Jahn O, Rhee J, Brose N (2010).
Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development.
Neuron 65, 358-372

Boutin C, Hardt O, de Chevigny A, Coré N, Goebbels S, Seidenfaden R, Bosio A, Cremer H (2010).
NeuroD1 induces terminal neuronal differentiation in olfactory neurogenesis.
Proc Natl Acad Sci U S A. 107, 1201-1206

Seuntjens E, Nityanandam A, Miquelajauregui A, Debruyn J, Stryjewska A, Goebbels S, Nave KA, Huylebroeck D, Tarabykin V (2009).
Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors.
Nat Neurosci. 12, 1373-1380

Gao Z, Ure K, Ables JL, Lagace DC, Nave KA, Goebbels S, Eisch AJ, Hsieh J (2009).
Neurod1 is essential for the survival and maturation of adult-born neurons.
Nat Neurosci. 12, 1090-1092

Robel S, Mori T, Zoubaa S, Schlegel J, Sirko S, Faissner A, Goebbels S, Dimou L, Götz M (2009).
Conditional deletion of beta1-integrin in astroglia causes partial reactive gliosis.
Glia 57, 1630-1647

Berman SB, Chen YB, Qi B, McCaffery JM, Rucker EB 3rd, Goebbels S, Nave KA, Arnold BA, Jonas EA, Pineda FJ, Hardwick JM (2009).
Bcl-x L increases mitochondrial fission, fusion, and biomass in neurons.
J Cell Biol. 184, 707-719

Hirrlinger J, Scheller A, Hirrlinger PG, Kellert B, Tang W, Wehr MC, Goebbels S, Reichenbach A, Sprengel R, Rossner MJ, Kirchhoff F (2009).
Split-cre complementation indicates coincident activity of different genes in vivo.
PLoS One. 4, e4286-e4286

Karram K, Goebbels S, Schwab M, Jennissen K, Seifert G, Steinhäuser C, Nave KA, Trotter J (2008).
NG2-expressing cells in the nervous system revealed by the NG2-EYFP-knockin mouse.
Genesis 46, 743-757

Brinkmann BG, Agarwal A, Sereda MW, Garratt AN, Müller T, Wende H, Stassart RM, Nawaz S, Humml C, Velanac V, Radyushkin K, Goebbels S, Fischer TM, Franklin RJ, Lai C, Ehrenreich H, Birchmeier C, Schwab MH, Nave KA (2008).
Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system.
Neuron 59, 581-595

Moers A, Nürnberg A, Goebbels S, Wettschureck N, Offermanns S (2008).
Galpha12/Galpha13 deficiency causes localized overmigration of neurons in the developing cerebral and cerebellar cortices.
Mol Cell Biol. 28, 1480-1488

Belvindrah R, Graus-Porta D, Goebbels S, Nave KA, Müller U (2007).
Beta1 integrins in radial glia but not in migrating neurons are essential for the formation of cell layers in the cerebral cortex.
J Neurosci. 27, 13854-13865

Goebbels S, Bormuth I, Bode U, Hermanson O, Schwab MH, Nave KA (2006).
Genetic targeting of principal neurons in neocortex and hippocampus of NEX-Cre mice.
Genesis. 44, 611-621

Monory K, Massa F, Egertová M, Eder M, Blaudzun H, Westenbroek R, Kelsch W, Jacob W, Marsch R, Ekker M, Long J, Rubenstein JL, Goebbels S, Nave KA, During M, Klugmann M, Wölfel B, Dodt HU, Zieglgänsberger W, Wotjak CT, Mackie K, Elphick MR, Marsicano G, Lutz B (2006).
The endocannabinoid system controls key epileptogenic circuits in the hippocampus.
Neuron 51, 455-466

Kashani AH, Qiu Z, Jurata L, Lee SK, Pfaff S, Goebbels S, Nave KA, Ghosh A (2006).
Calcium activation of the LMO4 transcription complex and its role in the patterning of thalamocortical connections.
J Neurosci. 26, 8398-8408

Wu SX, Goebbels S, Nakamura K, Nakamura K, Kometani K, Minato N, Kaneko T, Nave KA, Tamamaki N (2005).
Pyramidal neurons of upper cortical layers generated by NEX-positive progenitor cells in the subventricular zone.
Proc Natl Acad Sci U S A. 102, 17172-17177

Moosmang S, Haider N, Klugbauer N, Adelsberger H, Langwieser N, Müller J, Stiess M, Marais E, Schulla V, Lacinova L, Goebbels S, Nave KA, Storm DR, Hofmann F, Kleppisch T (2005).
Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory.
J Neurosci. 25, 9883-9892

Goebbels S, Bode U, Pieper A, Funfschilling U, Schwab MH, Nave KA (2005).
Cre/loxP-mediated inactivation of the bHLH transcription factor gene NeuroD/BETA2.
Genesis 42, 247-252

Brockschnieder D, Lappe-Siefke C, Goebbels S, Boesl MR, Nave KA, Riethmacher D (2004).
Cell depletion due to diphtheria toxin fragment A after Cre-mediated recombination.
Mol Cell Biol. 24, 7636-7642

Beggs HE, Schahin-Reed D, Zang K, Goebbels S, Nave KA, Gorski J, Jones KR, Sretavan D, Reichardt LF (2003).
FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies.
Neuron 40, 501-514

Kleppisch T, Wolfsgruber W, Feil S, Allmann R, Wotjak CT, Goebbels S, Nave KA, Hofmann F, Feil R (2003).
Hippocampal cGMP-dependent protein kinase I supports an age- and protein synthesis-dependent component of long-term potentiation but is not essential for spatial reference and contextual memory.
J Neurosci. 23, 6005-6012

Lappe-Siefke C, Goebbels S, Gravel M, Nicksch E, Lee J, Braun PE, Griffiths IR, Nave KA (2003).
Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination.
Nat Genet. 374, 366-374

Genoud S, Lappe-Siefke C, Goebbels S, Radtke F, Aguet M, Scherer SS, Suter U, Nave KA, Mantei N (2002).
Notch1 control of oligodendrocyte differentiation in the spinal cord.
J Cell Biol. 158, 709-718

Schwab MH, Bartholomae A, Heimrich B, Feldmeyer D, Druffel-Augustin S, Goebbels S, Naya FJ, Zhao S, Frotscher M, Tsai MJ, Nave KA (2000).
Neuronal basic helix-loop-helix proteins (NEX and BETA2/Neuro D) regulate terminal granule cell differentiation in the hippocampus.
J Neurosci. 20, 3714-3724

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