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Max-Planck-Gesellschaft
Max-Planck-Institut für Experimentelle Medizin
Publikationen
Snaidero N, Möbius W, Czopka T, Hekking LH, Mathisen C, Verkleij D, Goebbels S, Edgar J, Merkler D, Lyons DA, Nave KA, Simons M (2014).
Myelin Membrane Wrapping of CNS Axons by PI(3,4,5)P3-Dependent Polarized Growth at the Inner Tongue.
Cell 156, 277-290


Barrette B, Nave KA, Edgar JM (2013).
Molecular triggers of neuroinflammation in mouse models of demyelinating diseases.
Biol Chem. 394, 1571-1581


Richert S, Kleinecke S, Günther J, Schaumburg F, Edgar J, Nienhaus GU, Nave KA, Kassmann CM (2013).
In vivo labeling of peroxisomes by photoconvertible mEos2 in myelinating glia of mice.
Biochimie 98, 127-134


Ip CW, Kroner A, Groh J, Huber M, Klein D, Spahn I, Diem R, Williams SK, Nave KA, Edgar JM, Martini R (2012).
Neuroinflammation by cytotoxic T-lymphocytes impairs retrograde axonal transport in an oligodendrocyte mutant mouse.
PLoS One. 7, e42554-e42554


Fünfschilling U, Supplie LM, Mahad D, Boretius S, Saab AS, Edgar J, Brinkmann BG, Kassmann CM, Tzvetanova ID, Möbius W, Diaz F, Meijer D, Suter U, Hamprecht B, Sereda MW, Moraes CT, Frahm J, Goebbels S, Nave KA (2012).
Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity.
Nature 485, 517-521


Franklin RJ, Ffrench-Constant C, Edgar JM, Smith KJ (2012).
Neuroprotection and repair in multiple sclerosis.
Nat Rev Neurol. [Epub ahead of print]


Gruenenfelder FI, Thomson G, Penderis J, Edgar JM (2011).
Axon-glial interaction in the CNS: what we have learned from mouse models of Pelizaeus-Merzbacher disease.
J Anat. 219, 33-43


Ruest T, Holmes WM, Barrie JA, Griffiths IR, Anderson TJ, Dewar D, Edgar JM (2011).
High-resolution diffusion tensor imaging of fixed brain in a mouse model of Pelizaeus-Merzbacher disease: comparison with quantitative measures of white matter pathology.
NMR Biomed. 24, 1369-1379


Edgar JM, McCulloch MC, Montague P, Brown AM, Thilemann S, Pratola L, Gruenenfelder FI, Griffiths IR, Nave KA (2010).
Demyelination and axonal preservation in a transgenic mouse model of Pelizaeus-Merzbacher disease.
EMBO Mol Med. 2, 42-50


Edgar JM, Nave KA (2009).
The role of CNS glia in preserving axon function.
Curr Opin Neurobiol. 19, 498-504


orfini GA, Burns M, Binder LI, Kanaan NM, LaPointe N, Bosco DA, Brown RH Jr, Brown H, Tiwari A, Hayward L, Edgar J, Nave KA, Garberrn J, Atagi Y, Song Y, Pigino G, Brady ST (2009).
Axonal transport defects in neurodegenerative diseases.
J Neurosci. 29, 12776-12786


Edgar JM, McCulloch MC, Thomson CE, Griffiths IR (2008).
Distribution of mitochondria along small-diameter myelinated central nervous system axons.
J Neurosci Res. 86, 2250-2257


Roussarie JP, Ruffié C, Edgar JM, Griffiths I, Brahic M (2007).
Axon myelin transfer of a non-enveloped virus.
PLoS One. 2, e1331-e1331


Thomson CE, Hunter AM, Griffiths IR, Edgar JM, McCulloch MC (2006).
Murine spinal cord explants: a model for evaluating axonal growth and myelination in vitro.
J Neurosci Res. 84, 1703-1715


Andrews H, White K, Thomson C, Edgar J, Bates D, Griffiths I, Turnbull D, Nichols P (2006).
Increased axonal mitochondrial activity as an adaptation to myelin deficiency in the Shiverer mouse.
J Neurosci Res. 83, 1533-1539


Edgar JM, McLaughlin M, Yool D, Zhang SC, Fowler JH, Montague P, Barrie JA, McCulloch MC, Duncan ID, Garbern J, Nave KA, Griffiths IR (2004).
Oligodendroglial modulation of fast axonal transport in a mouse model of hereditary spastic paraplegia.
J Cell Biol. 166, 121-131


Edgar JM, Garbern J (2004).
The myelinated axon is dependent on the myelinating cell for support and maintenance: molecules involved.
J Neurosci Res. 76, 5-76


Edgar JM, McLaughlin M, Barrie JA, McCulloch MC, Garbern J, Griffiths IR (2004).
Age-related axonal and myelin changes in the rumpshaker mutation of the Plp gene.
Acta Neuropathol. 107, 331-335


Edgar JM, Anderson TJ, Dickinson PJ, Barrie JA, McCulloch MC, Nave KA, Griffiths IR (2002).
Survival of, and competition between, oligodendrocytes expressing different alleles of the Plp gene.
J Cell Biol. 158, 719-729


Edgar JM, Anderson TJ, Dickinson PJ, Barrie JA, McCulloch MC, Nave KA, Griffiths IR (2002).
Survival of, and competition between, oligodendrocytes expressing different alleles of the Plp gene.
J Cell Biol. 158, 719-729




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