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Max-Planck-Gesellschaft
Max-Planck-Institut für Experimentelle Medizin
Dr. Hauke Werner
Profile


Myelination of neuronal axons is beneficial, as it markedly accelerates the transmission of information in the nervous system. Indeed, the evolutionary innovation of myelin in ancient fish has facilitated the success of vertebrates. However, myelin is vulnerable to inflammation or genetic perturbation that affect its long-term integrity. This is best illustrated in acquired myelin diseases, heritable white matter disorders (leukodystrophies), or demyelinating neuropathies. The Research Group 'Neurochemistry' investigates the molecular and evolutionary mechanisms of myelination and the maintenance of myelin integrity. We combine the tools of mouse genetics, molecular cell biology, and biochemistry, including systematic proteome analysis, to study myelin in health and disease.


Main research interests


Myelin evolution
Myelin biogenesis
Myelin proteome analysis
Relationship between myelin structure and axonal function
Pathobiology of heritable white matter disorders (leukodystrophies)


Group leader


Dr. Hauke Werner
Research group ‘Neurochemistry’
Department of Neurogenetics
Max Planck Institute of Experimental Medicine
Phone +49-551-3899759
Fax +49-551-3899758
Mail hauke@em.mpg.de


Vita Hauke Werner


2014

Habilitation; University of Göttingen, Germany

2009-present

Lecturer in Neurobiology; BSc Biology and MSc Developmental, Neural, and Behavioral Biology; University of Göttingen, Germany

2008-present

Research Group Leader, Department of Neurogenetics, Max-Planck-Institute of Experimental Medicine, Göttingen, Germany

2003-2008

Research Fellow, Department of Neurogenetics, Max-Planck-Institute of Experimental Medicine, Göttingen, Germany (PI: Klaus-Armin Nave)

2001-2003

Postdoc, Department of Cell Biology, Yale University School of Medicine, New Haven, USA (PI: Pietro de Camilli)

2001

PhD (Dr. rer nat.) in Biology from the University of Heidelberg, Germany

 

 



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