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Max-Planck-Institut für Experimentelle Medizin
PD Dr. Hauke Werner

Myelination of neuronal axons is beneficial, as it markedly accelerates the transmission of information in the nervous system. Indeed, the evolutionary innovation of myelin in ancient fish has facilitated the success of vertebrates. However, myelin is vulnerable to inflammation or genetic perturbation that affect its long-term integrity. This is best illustrated in acquired myelin diseases, heritable white matter disorders (leukodystrophies), or demyelinating neuropathies. The Research Group 'Neurochemistry' investigates the molecular and evolutionary mechanisms of myelination and the maintenance of myelin integrity. We combine the tools of mouse genetics, molecular cell biology, and biochemistry, including systematic proteome analysis, to study myelin in health and disease.

Main research interests

Myelin evolution
Myelin biogenesis
Myelin proteome analysis
Relationship between myelin structure and axonal function
Pathobiology of heritable white matter disorders (leukodystrophies)

Group leader

Dr. Hauke Werner
Research group ‘Neurochemistry’
Department of Neurogenetics
Max Planck Institute of Experimental Medicine
Phone +49-551-3899759
Fax +49-551-3899758

Vita Hauke Werner


Habilitation; University of Göttingen, Germany


Lecturer in Neurobiology; BSc Biology and MSc Developmental, Neural, and Behavioral Biology; University of Göttingen, Germany


Research Group Leader, Department of Neurogenetics, Max-Planck-Institute of Experimental Medicine, Göttingen, Germany


Research Fellow, Department of Neurogenetics, Max-Planck-Institute of Experimental Medicine, Göttingen, Germany (PI: Klaus-Armin Nave)


Postdoc, Department of Cell Biology, Yale University School of Medicine, New Haven, USA (PI: Pietro de Camilli)


PhD (Dr. rer nat.) in Biology from the University of Heidelberg, Germany



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